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unexpected vision loss in a single or both eyes. Sudden vision decline in a single or both of those eyes could be a sign of a significant eye problem named non-arteritic anterior ischemic optic neuropathy (NAION).
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In the event the NO/cGMP pathway is activated, as takes place with sexual stimulation, inhibition of PDE5 by sildenafil leads to improved corpus cavernosum levels of cGMP . Hence sexual stimulation is required to ensure that sildenafil to make its meant advantageous pharmacological outcomes .
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